BDBM103737 US10206907, Compound 234::US11000528, Cpd # 11::US8563545, 11

SMILES FC1(F)CCN(Cc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)CC1

InChI Key InChIKey=PFKFICBDHPHHLW-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103737   

TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103737(US10206907, Compound 234 | US11000528, Cpd # 11 | ...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103737(US10206907, Compound 234 | US11000528, Cpd # 11 | ...)
Affinity DataIC50:  15.5nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In DepthDetails US Patent